One daily. Daily Probiotic Supplement. Daily care. Helps Defend Against Occasional: constipation; diarrhea; gas and bloating. 3 types of good bacteria to promote overall digestive health. Why: Why take Phillips' Colon Health? It helps replenish good bacteria when diet & travel upset your natural balance. To help support healthy colon, one of the most importance parts of your digestive system. To help support immune health. How: How does Phillips' Colon Health work? Contains a proprietary blend of 3 types of good bacteria: lactobacillus gasseri KS-13; bifidobacterium bifidum G9-1; bifidobacterium longum MM-2. When: When should you take products. Take one capsule daily. No refrigeration necessary. Can be taken in addition to laxative products. For more information about probiotics, go to www.phillipsdigestive.com. This product does not contain gluten. Questions or comments? Please call 1-800-986-0369 (Mon-Fri 9am-5pm EST). For more information about probiotics go to: www.phillipsdigestive.com. (This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.) Made in Japan.